LI Zhao-yong


Research Associate Professor
School of Life Sciences
University of Science and Technology of China
443 Huangshan Road, Hefei 230027, China
Tel: 86-551-63607012 (O);
Personal Profile
2012/9 -present,Research associate professor, University of Science and Technology of China
2010/3-2012/8,Research associate professor, Life Sciences Institute, Zhejiang University
2005/10-2008/8,Postdoctoral fellow, University of Massachusetts Medical School, USA
2002/9-2005/7,Ph.D. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
Research Interests
1. Function of non-coding RNAs
2. Regulation of cancer cell metabolism
Selected Publications
1. Li, Z.#, Huang, C.#, Bao, C.#, Chen, L., Lin, M., Wang, X., Zhong, G., Yu, B., Hu, W., Dai, L., Zhu, P., Chang, Z., Wu, Q., Zhao, Y., Jia, Y., Xu, P., Liu, H., and Shan, G*. Exon-intron circular RNAs regulate transcription in the nucleus. Nature structural & molecular biology, 2015, 22, 256-264. (Highlighted in Nature reviews. Molecular cell biology)
2. Wang S#, Xiang J#, Li Z#, Lu S, Hu J, Gao X, Yu L, Wang L, Wang J, Wu Y, Chen Z, Zhu H*.A plasma microRNA panel for early detection of colorectal cancer. International Journal of Cancer, 2015, 136:152-161. (#: co-first author)
3. Hassan MQ, Maeda Y, Taipaleenmaki H, Zhang W, Jafferji M, Gordon JA, Li Z, Croce CM, van Wijnen AJ, Stein JL, Stein GS, Lian JB*. miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells. Journal of Biological Chemistry, 2012, 287(50): 42084-42092.
4. Dai F, Shen T, Li Z, Lin X, Feng XH*. PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3. EMBO Reports, 2011, 12(11):1175-1181.
5. Li Z, Hassan MQ, Jafferji M, Aqeilan RI, Garzon R, Croce CM, van Wijnen AJ, Stein JL, Stein GS, Lian JB*. Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation. Journal of Biological Chemistry. 2009, 284(23):15676-15684.
6. Li Z, Hassan MQ, Volinia S, van Wijnen AJ, Stein JL, Croce CM, Lian JB*, Stein GS. A MicroRNA Signature for a BMP2-Induced Lineage Commitment Program. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(37):13906-13911.
7. Zhang Y, Hassan MQ, Li ZY, Stein JL, Lian JB, van Wijnen AJ, Stein GS*. Intricate Gene Regulatory Networks of Helix-Loop-Helix (HLH) Proteins Support Regulation of Bone-Tissue Related Genes during Osteoblast Differentiation. Journal of Cellular biochemistry, 2008, 105(2):487-496.
8. Li ZY#, Yang J#, Gao X#, Lu JY, Zhang Y, Wang K, Cheng MB, Wu NH, Zhang Y, Wu Z*, Shen YF*. Sequential recruitment of PCAF and BRG1 contributes to myogenin activation in 12-O-tetradecanoylphorbol-13-acetate induced early differentiation of Rhabdomyosarcoma-derived cells. Journal of Biological Chemistry, 2007, 282(26): 18872-18878.