GAO Xiaolian
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    GAO Xiaolian

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    Adjunct Professor, School of Life Sciences, USTC,

    443 Huangshan Road, Hefei 230027, China

    Tel: 86-551-63600705 or +1-713 743-2805

    E-mail: xgao@uh.edu

    Homepage: http://synbio.ustc.edu.cn

            http://gaolab.chem.uh.edu

    Personal Profile:

    2008-present  University of Science and Technology of China

    Adjunct Professor of synthetic biology

    2005-present University of Houston

    Professor of Biology & Biochemistry, adjunction appointment at Chemistry and Biomedical Engineering

    1992-1998, 1998-2002, 2002-2004University of Houston

    Assistant, Associate, and Professor of Chemistry, adjunction appointment at Biology and Biochemistry

    1990-1992 Glaxo Inc. Research Laboratories

    Senior Research Scientist and Research Investigator, Structural Biology

    1986-1989 Columbia University, Colleges of Physicians and Surgeons

    Postdoc & Associate Research Scientist, Biochemistry & Biophysics

    NMR of DNA and Ligand-DNA Complexes

    Research Advisor: Professor Dinshaw Patel

    1982-1986  Rutgers University, the State University of New Jersey

    Ph.D. in Chemistry  

    Synthesis and NMR Characterization of Isotope Labeled Oligodeoxyribonucleotides

    Research Advisor: Professor Roger A. Jones

    1978-1982  Beijing Institute of Chemical Engineering

    B.S. in Polymer Science

    Research Interests:

    Interdisciplinary areas of Chemistry and Biology. Areas of research focus include: (1) Chemistry for parallel synthesis of biopolymers on high density microfluidic biochips; (2) Biochip applications in genomics and proteomics; (3) Synthetic biology method development; (4) Biomolecular NMR spectroscopy for structure elucidation of nucleic acids, proteins, and their complexes with ligand molecules; Database for accelerating protein NMR spectral interpretation

     

    Selected Publications:

    1. Zhou Q, Li M, Wang X, Li Q, Wang T, Zhu Q, Zhou X, Wang X, Gao X, Li X. (2012) , Immune-related microRNAs are abundant in breast milk exosomes. Internatinal J. Biol. Sci. 8(1):118-23.
    2. Li. M. Z., Liu, Y., Wang, T., Guan, J., Luo, Z. Chen, H., Chen, L., Zhou, S., Ma., J., Mu, Z., Jiang, A.-A, Lang, Q., Zhou, X., Wang, J., Zeng, W., Li, N., Gao, X. Li, X. (2011) , Repertoire of porcine microRNAs in adult ovary and testis by deep sequencing. International J. Biol. Sci. 7(7):1045-55.
    3. Li M, Xia Y, Gu Y, Zhang K, Lang Q, Chen L, Guan J, Luo Z, Chen H, Li Y, Li Q, Li X, Jiang AA, Shuai S, Wang J, Zhu Q, Zhou X, Gao X, Li X. (2010) MicroRNAome of porcine pre- and postnatal development. PLoS One. 5(7):e11541
    4. Xia, Y., Yamaoka, Y., Zhu, Q., Matha, I., Gao, X. (2009) A Comprehensive sequence and disease correlation analyses for the C-terminal region of CagA protein of Helicobacter pylori. Plos Biology, 4, e7736.
    5. Gong, W., Zhou, D., Ren, Y., Wang, Y., Zuo, Z., Shen, Y., Xiao, F., Zhu, Q., Hong, A., Zhou, Z., Gao, X., and Li, T. (2008) PepCyber:P~PEP : A database of human protein-protein interactions mediated by phosphoprotein binding domains. Nucleic Acids Res. 36, D679-D683.
    6. Gu, P., Reid, J., Gao, X., Shaw, C. A., Creighton, C., Dugas, D. T., Tran, P. L., Zhou, X., Drabek, R., Steffen, D. L., Hoang, D., Weiss, M. K., Naghavil, A. O., El-daye, J., Kahn, M. F., Legge, G. B., Wheeler, D., Gibbs, R. A., Miller, J., Cooney, A. J., and Gunaratne, P. H. (2008) Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells. Plos ONE. 3, e2578.
    7. He, P. A., Nie, Z., Chen, J., Chen, J., Lv, Z., Sheng, Q., Zhou, S., Gao, X., Kong, L., Wu, X., Jin, Y. and Zhang, Y. (2008) Identification and characteristics of microRNAs from Bombyx mori. BMC Genomics 9, 248.
    8. Xiao, F., Zuo, Z., Cai, G., Kang, S., Gao, X. and Li, T. (2008) miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res.
    9. Wan, J., Kang, S., Tang, C., Yan, J., Ren, Y., Liu, J., Gao, X., Banerjee, A., Ellis, L. B. M., and Li, T. (2007) Meta-prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection. Nucleic Acids Res. In press.
    10. Feng, J., Wong, K.-Y., Lynch, G. C., Gao, X., and Pettitt, B. M. (2007) Peptide conformations of a microarray surface-tethered epitope of the tumor suppressor p53. J. Physical Chem. 111, 13797-13806.

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