Department of Microbiology and Immunology


I)About DMI

The Department of Microbiology and Immunology conducts research and provides training in forefront areas of microbiology, immunology, host-pathogen interaction, and related fields. Through such activities, our goal is to improve human and animal health as well as to improve our ability to be responsible stewards of a fragile earth. For Microbiology, Our long-term goal is to elucidate the small molecule-mediated signaling network and the regulatory mechanisms involved in quorum sensing, biofilm formation, and virulence, and to provide potential drug targets for treatment of bacterial infectious diseases. For Immunology, our major focus covers biology of NK/NKT cells, liver immunology, innate immunity and major diseases (cancer, infection and autoimmunity). We aim to understand the molecular and cellular mechanisms leading to the generation of several major immunologic diseases, and to develop effective gene immunotherapeutic strategies for treating them.

II) Principle Investigator

TIAN Zhigang

Research Interests

1.Biology of NK cells

2.Liver immunology

3.Innate immunity and major diseases (cancer, infection, and autoimmunity)


Research Interests

1.Innate immune recognition of natural killer (NK) cells

2.NK/NKT cells in liver injury and regeneration

LIAN Zhexiong

Research Interests

1.Basic liver immunology

2.Mechanism of autoimmune liver disease

3.Mechanism of autoimmune colitis

4.Autoimmune target therapy

WEI Haiming

Research Interests

1.Biology of human NK cells

2.Liver immunology

3.Innate immunity and major diseases  

SUN Baolin

Research Interests

1.Bacterial signaling and pathogenesis

2.Microbe-host interactions

XIAO Weihua

Research Interests

1.Signaling transduction and transcription in cancer

2.Signaling transduction and transcription in immune development and activation

3.Biological therapeutic drugs development, and mid-scale production


Research Interests

1.Contributions of different APCs to NKT cells function

2.Formation of immune synapse

3.NKT cells function in liver and adipose tissue inflammation.

III) Course

For undergraduate student

1.Medical immunology

2.Seminars on immunology and biomedicine


4.Experiments of immunology,


6.Introduction of biotechnology

7.Experimental biological products

For graduate student

1.Molecular immunology

2.Reading and analysis of latest immunological publications

3.Principle and application of immunological technology

4.Laboratory animal science

5.Molecular virology

6.Molecular immunology

7.Cell engineering

8.Cell laboratory method and principle

9.Medical biotechnology

10.Experimental process for biological pharmaceutical products

11.Advanced cell biology