2012.08.22,Professor Sun Fei Published a paper entitled:“Gold Nanoparticles Elevate Plasma Testosterone Levels in Male Mice without Affecting Fertility” in Small, online

  • 2012.08.22,Professor Sun Fei Published a paper entitled:“Gold Nanoparticles Elevate Plasma Testosterone Levels in Male Mice without Affecting Fertility” in Small, online
    Author:LI Wenqing、Wang Feng、Liu Zhiming、Wang Yucai、Wang Jun、Sun Fei

    DOI: 10.1002/smll.201201079

    Abstract

    ω-Methoxy and ω-aminoethyl poly(ethylene glycol)-modified 14-nm gold nanoparticles can accumulate in mouse testes, pass through the blood–testis barrier, and enter germ cells. Furthermore, PEGNH2@AuNP accumulate more easier in the testes and increase plasma T levels. 

    However, these two gold nanoparticle types have no effect on male fertility, fetal survival, or fetal development. 

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