HUANG Chengdong
[an error occurred while processing this directive]

    HUANG Chengdong

  •  

    HUANG Chengdong,Ph.D.
    Professor, School of Life Sciences
    University of Science & Technology of China
    443 Huangshan Street, Hefei City, Anhui 230027, P.R.China

    Education and Appointment:
    2017–present:  Professor, University of Science and Technology of China (USTC)
    2015-2017:   Postdoctoral Fellow, University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics
    2012-2015:   Postdoctoral Fellow, Rutgers University, Department of Chemistry and Chemical Biology,
    2010-2012:   Postdoctoral Fellow, Stony Brook University, Department of Biochemistry and Cell Biology
    2004-2010:   Ph.D., Auburn University, Department of Chemistry and Biochemistry
    2001-2004:   M.S., Dalian Institute of Chemical Physics, Chinese Academy of Sciences
    1997-2001:   Dalian University of Technology

    Areas of expertise:
    Biomolecular NMR spectroscopy, Structural biology, Molecular Machineries, Molecular Chaperone.

    Research Interest:
    Our current work primarily focuses on determination of the structural and dynamic basis for the function and assembly of large protein machineries.

    Honors & Awards: 
    2008-2010  Alabama EPSCoR GRSP Scholarship(Round 3, 4 and 5)
    2009-2010  Auburn University Outstanding Doctoral Graduate Award
    2009-2010  Graduate Council’s Outstanding Graduate Award, Department of Chemistry and Biochemistry, Auburn University
    2010       Award for Academic Excellence as Outstanding Graduate Student, Auburn University
    2010       Auburn University President's Award

    Selected Publications:
    1. Huang, Chengdong; Kalodimos, Charalampos, G. Structures of Large Protein Complexes by NMR. Annu. Rev. Biophys. (2017) 46, in press.
    2. Huang, Chengdong; Rossi, Paolo; Saio, Tomohide; Kalodimos, Charalampos, G. Structural basis for the antifolding activity of a molecular chaperone. Nature. (2016) 537, 202-206.
    3. Rath, Poonam; Huang, Chengdong; Wang, Tao; Wang, Tianzhi; Li, Huilin; Prados-Rosales, Rafael; Elemento, Olivier; Casadevall, Arturo; Nathan, Carl F. Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA. (2013) 110(49), E4790-4797.
    4. Huang, Chengdong*; Li, Guangtao*; Lennarz, William J. Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission. (*Equal contribution) Proc. Natl. Acad. Sci. USA (2012) 109(25), 9792-9297.
    5. Li, Guangtao*; Huang, Chengdong*, Zhao, Gang; Lennarz, William J. Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97. (*Equal contribution) Proc. Natl. Acad. Sci. USA (2012), 109(10), 3737-3741.
    6. Huang, Chengdong; Bhaskaran, Rajagopalan; Mohanty, Smita. Eukaryotic N-glycosylation Occurs Via membrane-anchored C-terminal domain of Stt3p subunit of oligosaccharyl transferase. J. Biol. Chem. (2012) 287(39), 32450-32458.
    7. Huang, Chengdong; Mohanty, Smita. Challenging the Limit: NMR Assignment of a 31 kDa Monomeric Helical Membrane Protein. J. Am. Chem. Soc. (2010), 132, 3662–3663.
    8. Huang, Chengdong; Mohanty, Smita, Bannerjee, Monimoy. A novel method of production and biophysical characterization of C-terminal domain of Stt3p, the catalyzing subunit of yeast Oligosaccharyl Transferase. Biochemistry (2010), 49, 1115–1126.

     

  • more