Department of Neurobiology and Biophysics
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    Department of Neurobiology and Biophysics

  • Introduction:

    The Department of Neurobiology and Biophysics was established in 1998as the 21st department of USTC and one of the first academic departments in Chinese universities with a neuroscience focus.The department currently consists of 15laboratories and 17active full-timefaculty members, with most PIs recruited from abroad in the past decade through the CAS “Hundred-Talent Program” and other national talent programs. The department has closecollaborations in both research and teaching with CAS Institute of Biophysics, Institute of Neuroscience, and Kunming Institute of Zoology, as well as Havard University, MIT, Johns Hopkins University, UCLA, University of Pittsburgh, CNRS,Netherlands Institute for Neuroscience and other first class international institutions.

    Research in the department spansmany areas of modernneuroscience, includingneural development, visual and auditory processing, synaptic plasticity and network dynamics; learning, memory and decision making; as well as mechanisms of related brain disorders including AD, depression and addiction. These studies combine molecular, cellular, electrophysiological, imaging, pharmacological, psychophysical and computational approaches using various model systems such as C elegans, zebrafish, mouse, rat, tree shrew and monkey. Faculty members in the department are also members ofthe CAS Key Laboratory of Brain Functionand Disease(KLBFD) and have access to cutting-edge imaging technologies atthe Center for Integrative Imaging (Cii) of the Hefei National Laboratory for Physical Sciences at the Microscale (HFNL). In addition, a new Center for Advanced Genetic Engineering is being established to provide unique primate research resources. Based on these research platforms, a common long-term goal of faculty research programs in the department is to dissect at multiple levels the neural circuit basis of key brain functions and diseases.

    Teaching is an import mission of the university. The department administrates9undergraduate courses including “Fundamental Neuroscience” and 11 graduate courses including “Principles of Neurobiology”, a new format course with lectures given primarily by leading scientists from CAS institutes and other universities.  Together with HFNL and KLBFD, the department also hosts seminar series, summer schools and workshops, as well as research symposiums where internationally renowned neuroscientists and biophysicists share their work.

    Faculty and Research Interests

    Primary Faculty (PIs):
    Bi Guoqiang   Neural plasticity, circuit analysis, imaging techniques
    Chen Lin    Central auditory information processing, tinnitus
    Hu Bing      Cell kinetics of neurodevelopment, repair of nerve injury
    Lau Pakming  Neural network dynamics, physiology of emotion and its disorder
    Liu Qiang    Non-coding RNA, energy metabolism, learning and memory and Alzheimer's disease
    Shen Yong    Molecular mechanism of AD and PD,drug discovery and new methods for diagnosis
    Song Xiaoyuan  lncRNAs,transcriptional regulation, chromosome interactions and senescence
    Wen Quan    Sensorimotor integrationin small animals, opticalneurophysiology, and computational neuroscience
    Xiong Wei    Ion channel modulation, synaptic function, drug design
    Xue Tian    Phototransduction, Non-image vision, Stem Cell, Photoreceptor Regeneration
    Yang Yupeng    Visual development and plasticity, amblyopia
    Zhang Xiaochu  Neural basis of decision making and addiction
    Zhang Zhi     Neural circuits underlying pain and emotional disorders
    Zhou Jiangning Molecular mechanism and diagnosis of AD and depression
    Zhou Yifeng   Aging and visual information processing, amblyopia

    Primary Faculty (co-PIs):
    Chen Jutao    Synaptic plasticity, adult neurogenesis, neurotoxicology
    Wang Ming   Synaptic plasticity and toxicoloty

    Distinguished Guest Faculty:
    Zhou Zhenghong
      Biological cryo-EM, trans-synaptic mechanisms of neurotropic viruses

    Teaching

    Undergraduate courses:
    Introduction to Life Sciences: Brain and Cognition
    Physiology
    FundamentalNeuroscience
    Experimental Physiology and Neurobiology(I, II)
    Neuroanatomy
    Pharmacology
    Cognitive Neuroscience
    Bioelectronics
    3D-Microscopyand Scientific Frontiers

    Graduate courses:
    Principles of Neuroscience (I, II)
    Advanced Neurobiology Experiments
    Molecular and Developmental Neurobiology
    Visual Neuroscience
    Auditory Neuroscience
    Synaptic Structure and Function
    Advances in Neural Plasticity
    Clinical Neurobiology
    Neuropharmacology and Toxicology
    Neuroscience LiteratureReading
    Neural Network and Its Application

     

  • Department of Neurobiology and Biophysics
  • Chair: Prof. BI Guoqiang
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